If you are using Keo cleats, there is a line on the cleat that you should use. My fitters all recommended putting the cleat on, then tightening it and going for a ride. If you feel you are ballet dancing, move the cleat forward 1 mm at a time until you feel full foot pressure. Same if you feel your heel is dropping when you try to put power on the downstroke. This is a real balancing act. Next is if you feel pressure on the inside or outside of your knee. This will require assistance from a professional fitter if you are not using Speedplay. Speedplay have (had) instructions on how to adjust ‘tilt’ on their site or there are YouTube videos.